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Proteins produced by the nervous system may be useful in the treatment of inflammatory disorders: research

 


Proteins produced by the nervous system may be useful in the treatment of inflammatory disorders: research

Proteins produced by the nervous system may help in the treatment of inflammatory diseases: Study & nbsp | & nbspPhoto Credit: & nbspiStock Image

Washington DC: The team of researchers may have found the key to treating inflammatory diseases such as asthma, allergies, chronic fibrosis, and chronic obstructive pulmonary disease (COPD).

In a study published in the journal Nature Immunology, researchers at Rutgers University found that a protein produced by the nervous system, neuromedin B (NMB), is involved in the prevention of excessive immune responses and damage of inflammation. discovered.

The immune response is the body’s ability to recognize and defend itself against harmful substances. The immune response can help get rid of the infection, but it can also cause inflammation if not properly limited.

Researchers have discovered that NMB proteins can stop the types of inflammation that occur in diseases such as asthma, allergies, chronic fibrosis, and COPD.

“For many years, the mechanisms that block the inflammatory response that the body heals after a worm infection are poorly understood,” said Mark C. Siracusa, lead author and associate professor at Rutgers New Jersey Medical School. “Our research provided an understanding and expectations for possible treatments with NMB, which have great potential for the treatment of inflammatory diseases such as asthma, allergies and COPD.”

COPD is the third leading cause of death among inflammatory diseases and allergies, and the sixth in the United States.

“Scientists previously believed that the immune system could regulate itself to resolve inflammation and prevent tissue damage. But new research suggests that the complex interactions between the immune and nervous systems may occur. It’s starting to become clear that the effects limit inflammation and promote health,” said Siracusa.

Patent applications for the Patent Cooperation Treaty (PCT) were submitted by the Rutgers Office of Research Commercialisation. The next step for researchers is to use this protein to develop drugs to treat diseases such as asthma, COPD, and allergies.

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