Health
Blood tests can find people at the highest risk of severe COVID-19
Wednesday, September 23, 2020 (HealthDay News)-New studies show that common blood markers may predict the severity of illness if you are unhappy to be admitted to the hospital with COVID-19 I will.
Blood markers are called the “Red Blood Cell Distribution Width” (RDW) -basically, the greater the dispersion of red blood cell size, the worse the patient’s prognosis, the study authors explain.
RDW test results for COVID-19 patients “highly correlate with patient mortality and include patient age, some other laboratory tests, and other identified risk factors such as some existing illnesses. Correlation persisted when controlled, “Jonathan Carlson of Massachusetts General Hospital (MGH) in Boston.
The new study was published online on September 23 JAMA Network Open It was led by Dr. John Higgins, a hospital pathologist and associate professor of systems biology at Harvard Medical School.
“We wanted to find a way to identify high-risk COVID patients as quickly and easily as possible. Which inpatients are most likely to be severely ill and may benefit from aggressive interventions. Is it likely to get worse sooner, “Higgins said in a hospital news release.
To that end, we examined blood tests on more than 1,600 adults diagnosed with SARS-CoV-2 infection who were admitted to one of four hospitals in the Boston area in March and April 2020.
Higgins and his team predicted that they might need to seek out some ambiguous blood markers that might predict bad results from COVID-19. However, they soon found that the RDW, which was already used in standard blood tests, easily met the bill.
In fact, researchers found that patients with RDW levels above the normal range when they were first admitted to the hospital were 2.7 times more likely to die than patients with test results in the normal range. Overall, 31% of patients with normal RDW test results died, compared to 11% of patients with normal RDW test results.
The study also found that if a patient’s RDW rate was normal at admission but then slowly began to exceed normal levels, it also correlated with increased patient mortality odds.
The next step for the Boston team is to discover why high RDW scores lead to worse results. “Such findings may indicate new treatment strategies or identify better markers of disease severity.
Dr. Teresa Murray Amat chairs emergency medical care on the Jewish Forest Hill on Long Island in New York City. Reading the new study, she said, “What we know is [health factors] Diabetes and hypertension are associated with worse outcomes, but there is still significant variability in symptoms and severity within those groups. “
Blood markers like the RDW, which can identify patients at risk, are very useful, Amato said.
“Elevated RDW may indicate poor overall health,” he said in any patient. Knowing whether a patient is at high risk of death shortly after admission, “you will be good at adjusting treatment in a scientific way to give the patient the best possible results,” Amato said. He said.
For more information
Centers for Disease Control and Prevention New coronavirus..
Source: Teresa Murray Amato, MD, Chair, Emergency Medicine, Long Island Jewish Forest Hill, New York. Massachusetts General Hospital, News Release, September 23, 2020
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