Health
Hong Kong scientists say antimicrobials have been successful against the coronavirus
Issuance:
Hong Kong (AFP)
Hong Kong scientists announced on Monday that affordable antibiotics used to treat gastric ulcers and bacterial infections are promising in the fight against the coronavirus in animals.
Researchers are investigating whether metallodrugs, a metal-containing compound that is more commonly used against bacteria, also have antiviral properties that can fight the SARS-CoV-2 coronavirus. I started.
Using Syrian hamsters as subjects, they discovered that one of the drugs, ranitidine bismuth (RBC), was a “potent anti-SARS-CoV-2 drug.”
“RBC can reduce the viral load in the lungs of infected hamsters by a factor of 10,” University of Hong Kong researcher Running Wang told reporters Monday.
“Our findings show that RBC is a potential antiviral agent for Covid-19.”
The coronavirus has killed more than one million people since it first appeared in China last December and has since spread around the world.
While scientists are scrambling to look for vaccines, they also have readily available drugs that may alleviate the symptoms caused by Covid-19 disease or help the body fight the infection. looking for.
Remdesivir, a widespread antiviral drug, and dexamethasone, a corticosteroid, have both been shown to have some success with the virus. Both were used by doctors to treat President Donald Trump after he was infected with Covid-19.
However, they have drawbacks.
Although remdesivir is expensive and globally deficient, dexamethasone has dangerous immunosuppressive effects for all but the most ill. Other drug cocktails have shown that liver damage can be a risk.
Scientists in Hong Kong said RBC is a commonly available drug used for gastric ulcer with a safe and comprehensive pharmacological profile.
“It’s been used for decades, so it’s pretty safe,” Wang said.
They added that their study, published in the journal Nature Microbiology, suggests that other metallodrugs may also be successful against the virus and need further investigation.
© 2020 AFP
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