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Short-term exercise significantly improves metabolic health: research

Short-term exercise significantly improves metabolic health: research

 


According to a Massachusetts General Hospital (MGH) study, short-term exercise can cause changes in body metabolite levels and help measure an individual’s cardiac metabolism, cardiovascular, and long-term health. There is.

In a study published in the journal Circulation, researchers said that approximately 12 minutes of acute cardiopulmonary exercise affected more than 80% of circulatory metabolites, including pathways associated with a wide range of good health outcomes. ..

Gregory Lewis, MD, Head of Heart Failure at MGH and Senior Author of the Study, said: “Although much is known about the effects of exercise on the body’s heart, blood vessels, and inflammatory system, our study is by associating specific metabolic pathways with motor response variables and long-term health outcomes. The effects of exercise. ”

“What impressed us was the effect of short exercise on the circulatory levels of biotransformers that control important physical functions such as insulin resistance, oxidative stress, vascular responsiveness, inflammation and longevity. . “

methodology

In this study, researchers collected data from the Flamingam Heart Study and measured levels of 588 circulatory metabolites before and after 12 minutes of strenuous exercise in 411 middle-aged men and women.

The research team identified favorable changes in some biotransformers that were previously shown to be associated with cardiovascular metabolic disorders at resting levels. For example, glutamate, an important metabolite associated with heart disease, diabetes, and reduced lifespan, was reduced by 29%.

Meanwhile, DMGV, a metabolite associated with an increased risk of diabetes and liver disease, decreased by 18%. The study also found that metabolic responses could be regulated by factors other than exercise, such as a person’s gender and obesity index.

Researchers at MGH have studied the long-term effects of metabolic signs of motor response to predict future states of individual health and how long they may live.

“We are beginning to better understand the molecular basis of how exercise affects the body, and we are using that knowledge to understand the metabolic structures around motor response patterns.” Faculty of Cardiology, MGH.

“This approach has the potential to target people with high blood pressure and many other metabolic risk factors in response to exercise and put them on a healthier trajectory early in their lives,” he said. Added.

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