Male contraceptives are scheduled to begin clinical trials in humans this year | SmartNews

Most contraceptives are designed for people with a uterus, and people with testicles have few options for preventing pregnancy. Scientists are currently working on the creation of non-hormonal contraceptives for men, which have proven successful in rodent laboratory tests.According to the researchers behind contraceptives, human clinical trials End of the year..

“Women have many options for contraception, from pills to patches to intrauterine devices, and as a result, bear most of the burden of preventing pregnancy,” the study behind the study said. Said: Press release.. “But men’s contraceptive options, and therefore responsibilities, may soon expand.”

A new pill created by a team at the University of Minnesota blocks proteins from binding to vitamin A. It is known to be essential for the fertility and vitality of mammals. GizmodoEdkara. According to a study published this week at the American Chemical Society’s annual meeting, the drug is 99% effective in preventing pregnancy in mice and has no obvious side effects.

After oral administration to mice for only 4 weeks, sperm count decreased sharply and became sterile. When the team stopped taking the drug, they noticed that the effect of the drug was reversed: the mice returned to normal vitality in 4 to 6 weeks.

Depending on the results of human trials, the drug could quickly become the first effective form of contraception for people with testicles, except for condoms and surgery, Hannah So reports. To do Popular science..

“Scientists have been working on developing effective oral contraceptives for men for decades, but there are no approved tablets on the market yet,” said Minnesota, who was involved in the development of the tablets. University chemist Md Abdullahal Noman said: Press release..

Because this contraceptive is non-hormonal, it may have fewer side effects. Early attempts at male contraceptives worked primarily by blocking testosterone. This can lead to depression, weight gain and loss of libido. Rodents seemed to be doing well, even when scientists overdose the new drug in mice.

“The compound showed no toxicity when even taken to a dose 100 times the effective dose,” Norman says, Alex Wilkins. New Scientist..

Researchers emphasize that the success of the drug in rodents does not guarantee the same results in humans. Therefore, scientists are watching carefully. Human clinical trials It is scheduled to start later this year.

Medical professionals hope that these recent advances in male contraception will allow people of all genders to manage their reproductive health. Another male contraceptive, I rubbed the gel on my shoulder We are currently in clinical trials every day.

“Our track record as a gender to take responsibility for contraception is not great. Women are surgically sterilized, even though tubal ligation in women is much more invasive than vasectomy. By undergoing surgery, we are overwhelmingly superior to men, “says Jesse Mills, director of the UCLA Men’s Clinic, who was not involved in the study. Health line.. “I want to see what human clinical trials show.”

Recommended videos

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos