Health
Each COVID-19 reinfection increases health risk
July 7, 2022 – A large national database study shows that people who are re-infected with the virus that causes COVID-19 are at increased health risk with each reinfection.
Researchers have confirmed that the health effects worsen during active infections, but some symptoms last for 6 months and are re-infected. Long COVID..
“Reinfection adds or contributes to additional health risks. People should strive to avoid reinfection as it is not completely benign,” said lead research author Ziyad Al-Aly, MD. ..
The risk remained whether or not people were completely vaccinated. In some cases, people may have been previously infected with the Delta strain and are now exposed to Omicron or its subvariant BA.5. vaccination Protection, he says.
“The first infection may have weakened some organ systems, making people more vulnerable to health risks when they receive a second or third infection,” a study by a clinical epidemiologist at the University of Washington. The responsible person, Al-Aly, adds. VA St. Louis Healthcare system development. “Although various factors are involved, it is clear that reinfection poses an additional risk and should be avoided.”
Al-Aly and his colleagues compared the first 257,427 people infected with the virus that causes COVID-19 to a group of 38,926 people infected after the second, and then to 5.4 million people who had never been infected. Did. The information in this study comes from veterans in the Department of Veterans Affairs medical database.
The results were published online on June 17th. Preprint surveyThat means it hasn’t been peer-reviewed yet. This is an important step to help evaluate and validate clinical studies.The study is being reviewed by the journal Nature portfolio..
Experts participate
Three COVID-19 experts who were not involved in the study raised some warnings, such as how the veterans’ study applies or does not apply to the general public.
“This is the first study to characterize the risk of reinfection,” says Dr. Eric Topol.
He points out that the second infection is associated with twice the rate of deaths from any cause and twice the risk of heart and lung problems compared to the first. ..
Topol, executive vice president of Scripps Research and editor-in-chief of Medscape, WebMD’s sister site for healthcare professionals, said that each infection increases the additional risk.
“Obviously, these findings are worrisome because reinfection was very rare and less than 1% before the Omicron wave hit. Delta variant wave. But now reinfection is much more common, “he says.
Higher risk, especially for some
When asked to comment, the study “did well,” says Dr. Ali Mokudad. Al-Aly and his colleagues “have access to excellent data and have done some research.”
He says the extra risk is more likely among the elderly, immunocompromised, and people with other medical conditions.
“It makes sense, so let me explain why,” says Mokudad. It also causes more damage. “
Mokudad, an assistant professor of epidemiology at the University of Washington at Seattle and a professor of health indicator science, said:
“For you and the general public, whether healthy or chronic, the best thing is not to get infected,” he says. “Get vaccines and boosters and wear a mask when you’re in a crowded area where you can’t keep a safe distance.”
Are the risk factors for veterans different?
“The big caveat when looking at the study is that veterans don’t look like the average person,” said Ameshua Dalha, MD, senior scholar at the Johns Hopkins Health and Security Center at the Bloomberg School of Public Health in Baltimore. say.
“I don’t think you can generalize [the study] For everyone, but for those who actually have risk factors for serious illness, “he says.
He says many re-infected people are positive at home. As a result, their case is not research. In contrast, the veterans in this study were “people who for some reason wanted to take a formal exam.”
Shot can still be protected from serious illness, hospitalization, and death, but not from infection, because the virus has mutated from the vaccine, says Adalja. “This is also true for previous immunity. For example, a person infected with BA.1 or Delta may not be very capable of dodging the new variants BA.4 and BA.5.”
This study shows why it is important to have the latest information on vaccines and why it is necessary to obtain better vaccines targeting the mutants currently on the market.
Despite these warnings, researchers used a “robust database” and a large research group. This gives us all the confidence in the strength of our discoveries.
See long-term impact
It was unclear whether reinfection contributed to an increased risk of long-term COVID, so researchers Al-Aly and colleagues followed veterans for six months. They compared people with one, two, three, or more infections with the uninfected group.
Of the re-infected persons, about 13% were infected twice, 0.76% three times, 0.08%, that is, 246 people were infected four times or more.
Re-infected veterans were more than twice as likely to die for any reason as compared to the first coronavirus-infected veterans.
“While the mechanisms behind the increased risk of death and adverse health effects of reinfection are not entirely clear, findings highlight the consequences of reinfection and emphasize the importance of preventing reinfection. SARS -CoV-2, “The virus that causes COVID-19.
Asked about the next steps in the study, Al-Aly said, “BA.5 seems to be the main challenge looming and we are focused on better understanding it.”
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Sources 2/ https://www.webmd.com/lung/news/20220707/each-covid-19-reinfection-increases-health-risks The mention sources can contact us to remove/changing this article |
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