Health
Influenza virus may have marine origin with fish as primary host
A new study (not yet peer-reviewed) published as a preprint in Bio Rxiv the order ArticulavirusesThis includes the influenza virus, which first emerged in aquatic ecosystems, and fish may have been early hosts for the influenza virus. The study found that invertebrates, not fish, were likely the original hosts of the influenza virus.
This study found that influenza virus can infect all classes of fish and Siberian sturgeon ( bath reciprocator) may have served as an early host, if not the first, for influenza viruses before they spread to mammals.
In addition to its aquatic origin, the researchers said: Articulaviruses It may have been around since corals branched off to form other members about 640 million years ago. Articulaviruses of other animals.
street nature news Mary Petrone, a virologist at the University of Sydney in Australia and the first author of the preprint, analyzed the RNA of two coral species and found evidence of viral infection. The discovery of the virus in coral provided the first hint that the influenza virus may have originated in the ocean.
The identification of a distant relative of influenza in hagfish in 2018 only strengthened the possibility of a marine origin for the virus.
Researchers who found the virus in two species of coral turned their attention to Siberian sturgeon and surprisingly found evidence of the virus in sturgeon fish. “Phylogenetic analysis of the three polymerase segments revealed that sturgeon-related viruses consistently fall within the influenza clade, but underlie all known influenza viruses,” they write.
“The discovery of two early strains of influenza suggests that influenza probably infected aquatic animals, including fish, before it traveled to land,” said Dr. Petrone. nature news.
“initial host”
The researchers emphasized this point in preprints, with fish serving as early hosts for the influenza virus. They said: “Our findings suggest that influenza viruses can infect all classes of fish, and that these animals were among the first, if not the first, to spread to mammals. It may have served as a host for the influenza virus.”
virus inside Articulavirales The order “utilizes a large repertoire of transmission paths.” If the influenza virus spreads through respiratory droplets in mammals or via bird faeces, transmission of the virus from one fish to another is thought to occur via the respiratory route.
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