A 2018 paper confirmed damage to the macula (center of the retina) in people who took the drug for an average of 15 years. Further research in 2019 confirms that people taking pentosan polysulfate may develop pigment in the retina and threaten vision.
Health
Interstitial cystitis drugs can affect the macula of the eye. To your health
The lawsuit alleges that the drug company withheld knowledge of this potential side effect.
People with IC should be aware of this potential side effect. People with visual symptoms should have a visual examination by an ophthalmologist. The risk of retinal damage was highest in those who took the most elmirones, and 42% of those who took the most elmirons over the years had evidence of this toxicity.
Although there is no official recommendation, I think that people who have been taking Elmiron for many years should have an eye exam. Knowing if there is toxicity is important in deciding whether to continue taking the drugEspecially because there is evidence that damage can continue even after the drug is stopped. Despite this toxicity, people may still choose to continue medication. When Vioxx was removed from the market, I think many of my patients wanted to continue it despite the risks. Knowing the risks is essential to making informed decisions..
Dear Dr. Roach • What do you think about the enema epidemic? I’ve heard stories of people doing enema every day. Some even go to a doctor for higher irrigation. This is strange to me and I don’t think I’m healthy. — L.
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