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Exposure to air pollution during pregnancy increases flu risk

Exposure to air pollution during pregnancy increases flu risk

 


Pregnant women can get severe respiratory infections from multiple viruses, including influenza A virus (IAV), respiratory syncytial virus (RSV), and severe acute respiratory syndrome coronavirus (SARS-CoV-2). easier. In addition, pregnant women are disproportionately affected by influenza, resulting in a more than 10-fold increased risk of hospitalization for her.

A new study led by Dr. Natalie Johnson, associate professor in the Department of Environmental and Occupational Health at Texas A&M University School of Public Health, shows that exposure to ultrafine particles (UFPs) during pregnancy increases the risk of respiratory viral infections. increase. The results of this study recently Particle and fiber toxicology.

“We know that air pollution affects the immune system in the lungs, making them more susceptible to viral infections,” Johnson said. “We also know that pregnant women are already at higher risk of severe flu.” Surprisingly, the study did not investigate the combined effects of pregnancy, air pollution and influenza.Our findings suggest that these interactions need to be further studied to prevent short-term and possibly long-term effects. – long-term effects on maternal health.”

In this study, Johnson and her coauthors point out that there are several physiological features that explain maternal susceptibility to viral infections. Among them are increased cardiac output and decreased tidal volume (the amount of air that moves in and out of the lungs with each respiratory cycle), and selective regulation of immune cell subsets to protect the developing fetus. immunological changes such as

The research team also highlighted that although vaccination against influenza is safe and effective, vaccination compliance during pregnancy is generally less than 50%, increasing the risk of developing respiratory infections. doing.

As a result, air pollution, a global environmental health problem, is responsible for 1 in 9 deaths and causes more than 7 million premature deaths annually. Mixtures of gas and small airborne particulate matter, classified as UFPs, are important to recognize and identify to protect particularly vulnerable populations.

The research team says these findings support future clinical and regulatory interventions to protect pregnant women and control UFP. According to researchers, it is imperative that pregnant women in urban areas where influenza and UFP are endemic are given vaccinations and precautions that limit UFP exposure to protect maternal health.

“Air pollution is a pervasive environmental health problem,” Johnson said. “Strategies that protect the most vulnerable, such as pregnant women, are paramount to reducing adverse health impacts.”

Additional authors include Nicholas L. Drury, Texas A&M Environmental and Occupational Health Service, and Texas A&M Nutrition Service. Toriq Mustapha, Texas A&M Department of Environmental and Occupational Health. Ross A. Shore, Texas A&M Department of Environmental and Occupational Health, Jiayun Zhao, Texas A&M Chemical Division. Gus A. Wright, Texas A&M Department of Veterinary Pathology. Aline Rodrigues Hoffmann, Department of Comparative, Diagnostic, and Population Medicine, University of Florida. Susanne U. Talcott, Texas A&M Nutrition Office. Annette Regan, University of San Francisco School of Nursing and Health. Robert M. Tighe, Duke University School of Medicine. and Lenny Zhang, Texas A&M Chemistry Division and Texas A&M Atmospheric Science Division.

Sources

1/ https://Google.com/

2/ https://www.sciencedaily.com/releases/2023/04/230419201708.htm

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