Antibodies in blood samples of individuals who experienced a breakthrough COVID-19 infection were 1,000% more effective than antibodies produced two weeks after the second Pfizer vaccine dose. Journal of American Medical Association..
Scientists at the Portland-based Oregon Health & Science University collected blood samples from 52 Pfizer-vaccinated university personnel. Of the 52, 26 had mild breakthrough infections after vaccination. Of the groundbreaking cases, 10 were identified as delta variants, 9 as non-delta variants, and 7 as unknown variants.
Researchers have found that individuals with breakthrough cases produce more antibodies at baseline, and those antibodies are substantially superior in neutralizing live viruses. ..
The results suggest that breakthrough infections generate a strong immune response against delta mutants. The authors state that the findings suggest that the immune response is likely to be very effective against other mutants as well.
This study suggests that each post-vaccination exposure helps enhance the immune response to subsequent exposure to new variants of the virus.
“No further immune response can be obtained,” said Dr. Fikadu Tafes, senior author and assistant professor of molecular microbiology and immunology at OHSU School of Medicine on December 16. news release.. “These vaccines are very effective against serious illnesses. Our study suggests that individuals exposed to breakthrough infections after being vaccinated have hyperimmunity. increase.”
“I think this marks the end of the game,” said co-author Marcel Carlin, MD, Associate Professor of OHSU School of Medicine, and Medical Director of OHSU Occupational Health. “It doesn’t mean we’re at the end of the pandemic, but it does indicate where we’re likely to land. If we’re vaccinated and then exposed to the virus, it’s probably going to work pretty well- Protected from future variants. “
“We have not specifically investigated the Omicron variant, but based on the results of this study, breakthrough infections from the Omicron variant produce an equally strong immune response among vaccinated people. I expect, “said Dr. Tafes.
“The key is to get vaccinated,” said Dr. Carlin. “You must have a foundation of protection.”
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2/ https://www.beckershospitalreview.com/public-health/people-may-have-super-immunity-after-breakthrough-covid-small-study-suggests.html
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