Health
Severe COVID-19 during pregnancy is almost exclusively restricted to unvaccinated females – when to change policy
There seems to be little incentive to change this among regulators and pharmaceutical companies. Exacerbated by their exclusion, there is considerable vaccine hesitation among pregnant women.
Such hesitation continues, despite the increasing adverse consequences of SARS-CoV-2 infection among pregnant and postnatal women in many countries.
These have been improved in most other groups. The effects of the Omicron variant are still unknown.
We have identified three factors that influence the acceptance of vaccines for parents or their children. Confidence in vaccine efficacy, confidence in medical professionals, and, importantly, the certainty of a system for assessing vaccine safety.They say dealing with vaccine hesitation is a “complex problem”. [which] A multi-level approach is needed, including interventions at the individual and healthcare system levels. “
However, in many countries, pregnant and postpartum women and women planning to become pregnant continue to receive conflicting messages, primarily regarding vaccine safety. Misleading information on social media hinders the uptake of vaccinations in pregnant and postpartum women, even though observational data on the safety of vaccines, which currently include more than 250,000 women, are very reassuring. I’m continuing.
In addition, obvious potential benefits such as placental infection of protective antibodies to the fetal are documented.
By preventing maternal illness, vaccination can prevent stillbirth, preterm birth, and associated neonatal death.
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Several European countries (Norway, UK) have recently recognized pregnant and postpartum women as a “risk” priority group for COVID vaccination. This policy has long been in place in other countries (Belgium, Denmark), but it is still not universal (for example, in Italy, the Netherlands and Finland, pregnant women are not prioritized).
We were able to combine surveillance data from six countries. This indicates that among the most severely ill pregnant and postpartum females, few have been vaccinated (table 1). This is observed despite the large differences in the intake of artificial vaccines.
table 1Hospitalization of symptomatic pregnant women and life-saving emergency with estimated vaccine intake, 6 European countries, May-December 2021.
Not applicable-data not available
Our findings give the message that vaccination of unvaccinated pregnant women, their partners, medical professionals, decision makers and politicians who care for pregnant women protects them from serious illness. I’m emphasizing. To provide protection against severe COVID-19, especially in vulnerable groups such as pregnant and pregnant, as the world is entering a new phase of the COVID pandemic and the delta variant is rapidly overtaken by the omicron variant. Booster vaccination is becoming more and more important. Postpartum females or women who want to become pregnant. However, many pregnant and postpartum women in low-income, middle-income, and high-income environments have not yet been vaccinated once. Currently, there is a clear need for a healthcare system and individual actions. The World Health Organization recommends COVID-19 vaccination of pregnant women if the benefits of vaccination of pregnant women outweigh the potential risks. These multilateral data underscore these benefits in terms of prevention of serious illness. We believe that all governments should now prioritize pregnant and postpartum women as a group at risk and encourage vaccination.
Declaration of competing interests
Hilde Engjom reports funding and travel expense reimbursement from the Nordic Society of Obstetrics and Gynecology (NFOG) Research Fund as a keynote speaker invited at the annual meeting of the Norwegian Perinatal Society in November 2021. .. Marian Knight reports funding from the National Institute or Health Research, Medical Research Council and Women’s Happiness. Thomas van den Akker reports funding from the Medical Research Council and the Laerdal Foundation. Anna Aabakke reports funding from a shared fund for a joint health research project in the Southern Denmark region and regional Zeland, and is the head of the Board of Education of the Danish Society of Obstetrics and Gynecology (DSOG). Outi Ayras reports funding from the Finnish Medical Foundation and the Nordic Obstetrics and Gynecology Federation. Kitty Bloemenkamp reports infections of the INOSS network from the European Medicines Agency (EMA) “COVID-19 Infections During Pregnancy and Drugs During Pregnancy”. Serena Donati reports on funding from the Istituto Superiore di Sanità (National Institute of Health, Italy). Danilo Cereda and Evelien Overtoom are not interested in declaring.
Acknowledgments
The author would like to thank all the reporting clinicians, research and management teams for the contributions that made the INOSS study impossible.
Contributor
Marian Knight: UK and International Research Design, UK Data Collection, Data Interpretation and Writing. Kitty Bloemenkamp: Research Design Netherlands and International, Data Collection Netherlands, Data Interpretation and Writing. Serena Donati: Italian and international research design, Italian data collection, data interpretation and writing. Danilo Cereda: Italian research design, data collection Italy, data interpretation and writing. Thomas van den Akker: Dutch research design, Dutch data collection, data interpretation and writing. Evelien Overtoom: Research Design Netherlands, Data Acquisition Netherlands, Data Interpretation and Writing. Anna Aabakke: Danish Research Design, Data Collection Denmark, Data Interpretation and Writing. OutiÄyräs: Finnish research design, Finnish data collection, data interpretation and writing. Hilde Engjom: Norwegian research design, data acquisition Norway, data interpretation and writing.
appendix. Supplementary material
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Published: January 26, 2022
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