Studies: Even 2-3 glasses of beer a week can cause brain changes, cognitive decline

New studies suggest that even moderate drinking may be associated with brain changes and cognitive decline. Photo courtesy of Africa Studio / Shutterstock.com

July 14th (UPI)- Moderate drinkers faced cool news from a large British research study on Thursday: even absorption of that amount may be associated with brain changes and cognitive decline.

Specifically, drinking 7 or more “units” of alcohol per week increases iron levels in the brain. Iron accumulation is associated with Alzheimer’s disease. ParkinsonIllness. It is also seen as a potential mechanism of alcohol-related cognitive decline.

according to it study Approximately 21,000 people published in the journal PLOS Medicine on Thursday.

“Importantly, this is the first study to show high iron levels in the brain, which is associated with cognitive decline in” moderate “drinkers,” said the lead author of the study. Anya Topiwala told UPI by email.

Topiwala, a senior clinical researcher at the Nafield School of Population and Health at Oxford University in the United Kingdom, said:

Topiwala explained how modest a person’s alcohol intake should be to avoid adverse health effects.

One unit of alcohol in the United Kingdom is defined as 8 grams (10 milliliters) of pure alcohol / ethanol. “That is, seven units are about two large 250 ml glasses, 14% wine or 2-3 bottles of beer a week,” she said.

In this study, alcohol consumption above 7 units per week was associated with markers of high iron in groups of brain regions involved in the control of basal ganglia, motor movements, procedural learning, eye movements, cognition, emotions, etc. I found out. According to a news release about the research.

“I didn’t think we could find any evidence of high iron levels in the brain at such low levels of drinking,” Topiwala said, adding that the results were surprising.

In fact, the study found much higher levels of drinking among 20,965 participants. Participants self-reported the amount. The method, which researchers said was necessary for such a large group, admitted that it would probably lead to underreporting.

According to a news release, 2.7% are proud to be non-drinkers, but the average intake is about 18 units per week, which is equivalent to about 7½ cans of beer or 6 large glasses of wine. ..

All participants in the study (part of a biomedical database of 500,000 people in the UK called the UK Biobank) performed brain scans using magnetic resonance imaging. Nearly 7,000 people also had MRI scans of the liver to assess systemic iron levels.

All participants also completed a series of tests to assess cognitive and motor function. Their average age was 55, even divided between men and women.

Centers for Disease Control and Prevention in the United States Point to Federal Dietary Guidelines for Americans from 2020 to 2025 on Safe Levels of Alcohol Intake.

The guidelines recommend that adults who choose to drink should “drink moderately, limiting the number of drinking days to 2 or less per day for men and 1 or less per day for women.”

The CDC states that two in three adult drinkers report drinking above moderate levels at least once a month.

Topiwala said the idea of ​​focusing on iron accumulation was interesting to her because it wasn’t previously considered by “medium” drinkers.

“In addition, there are medicines that can lower the level of iron in the body, so if iron proves to be the cause of the damage, there may be ways to reduce the damage,” she explains. ..

Topiwala said researchers did not measure iron directly in the brain, but analyzed other aspects of the brain scan, such as changes in the magnetic field that are generally associated with changes in iron.

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