Coronavirus reinfection causes immune concerns

Amsterdam/Brussels (Reuters)-Concerns about people’s immunity to coronavirus as two European patients are confirmed to be reinfected with COVID-19 and the world is struggling to control the pandemic Is occurring.

Cases in Belgium and the Netherlands follow a report by researchers in Hong Kong this week about a man infected with another virus strain four and a half months after being declared recovered-the first such second infection was documented. Be converted.

Experts have raised concerns about the efficacy of potential vaccines against the virus, although more reinfections would be needed for these to be justified.

Belgian virologist Mark Van Ranst said the Belgian case was a woman who first became infected with COVID-19 in March, and then in June with another coronavirus strain. In addition, cases of reinfection are likely to surface, he said.

Van Lanst told Reuters TV that women in their 50s had few antibodies after the first infection, but they may have limited disease. Reinfection cases were probably a limited exception, he said, too early to tell, and many are likely to emerge in the coming weeks.

The new coronavirus appeared more stable than the influenza virus, but it was changing, he added.

“The virus is mutating, which means that a potential vaccine will not last forever for 10 years, perhaps even 5 years. Like influenza, this has to be redesigned fairly regularly. It won’t be,” he said.

Van Ranst, who works for several COVID-19 committees in Belgium, said vaccine designers would not be surprised.

“We wanted the virus to be more stable than it is now, but we can’t force nature.”

Genetic testing

The Dutch National Institute of Public Health said it had also observed Dutch cases reinfected with another strain of the virus.

“It’s clear that there were first and second infections with a significant amount of the virus. It was shown that the viruses were actually different enough to determine the genetic code of the virus.” Said Marion Koopmans, a leading Dutch virologist and member of the World Health Organization’s Scientific Advisory Group.

She added that older Dutch patients had a weakened immune system, which explained the patient’s situation. “People are worried and ask if the reinfection is “normal”. I don’t think so,” she added.

Margaret Harris, a WHO spokesperson, told the United Nations briefing about the Hong Kong case in Geneva, although there are case reports of reinfection, but having clear documentation is important.

Some experts say that such cases are likely to begin to emerge because the virus is not spreading differently, but because more testing has been done around the world. ..

Still, Dr. David Strain, senior clinical lecturer at the University of Exeter and chairman of the Medical Academy Committee of the British Medical Association, said the case was worrisome for at least two reasons.

“The first suggests that previous infections are not protective. The second is to increase the likelihood that vaccination will not provide the hope we have been waiting for.”

Reported by Toby Sterling and Anthony Deutsch in Amsterdam, Philip Blenkinsop, Bart Biesemans, Christian Levaux in Brussels, Stephanie Ulmer-Nebehay in Geneva, and Josephine Mason in London. Edited by Christopher Cushing, Alex Richardson, Mark Heinrich

Our criteria:Thomson Reuters Trust Principles.

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