Post-Covid-19 Inflammatory Syndrome Causes Severe Damage to Children’s Hearts: A Study

According to a review of the studies, the childhood inflammatory syndrome, thought to be associated with Covid-19, can damage the heart enough that some children require lifelong monitoring and intervention.

Research published in journals Clinical medicine, Assessing more than 600 case studies of multisystem inflammatory syndrome in children (MIS-C) and being able to attack seemingly healthy children without warning 3-4 weeks after asymptomatic Covid-19 infection Revealed.

“According to the literature, children did not have to exhibit the classic upper respiratory symptoms of Covid-19 in order to develop the dreaded MIS-C,” said co-author of the study, University of Texas San Antonio Health Science Center Alvaro Moreira said. In the United States.

“The children may be asymptomatic, no one might know they were sick, and after a few weeks, they might develop this exaggerated inflammation in the body. “

In this study, scientists reviewed 662 MIS-C cases reported worldwide from January 1 to July 25, with 71% of children admitted to an intensive care unit (ICU). I have found that.

They said that 60% of children had an exacerbated immune response, with an average hospital stay of 7.9 days.

According to scientists, all 662 children had fever, 73.7% had abdominal pain or diarrhea, and 68.3% had vomiting.

They stated that 90% had an echocardiography (EKG) cardiac scan and found 54% of the results were abnormal.

The study states that more than one-fifth of the children needed a ventilator and 11 children died.

“This is a new childhood disease that is thought to be associated with SARS-CoV-2,” Moreira said.

“It can be fatal because it affects multiple organ systems. There were many aspects, such as the heart, lungs, digestive system, and nervous system, which were initially difficult for clinicians to understand. He added.

The researchers pointed out that the amount of MIS-C inflammation was greater than two similar childhood pathologies in which the immune response was exacerbated-Kawasaki disease and toxic shock syndrome.

“The benefit of the savings was that treating these patients with treatments commonly used for Kawasaki-immunoglobulins and glucocorticosteroids-was effective,” Moreira said.

The study found that most of the 662 children suffered from heart failure, as shown by troponin and other marker molecules in the body used to diagnose heart attacks in adults.

“Almost 90% of the children (581) had echocardiography because they had these prominent symptoms of heart disease,” Moreira said.

Scientists have found dilation of coronary blood vessels in children-a phenomenon was also seen in Kawasaki disease.

They also observed a reduced ejection fraction-demonstrating a reduced ability of the heart to pump oxygenated blood into the body’s tissues.

The study said that approximately 10 percent of children had coronary aneurysms.

“This is the local stretching or swelling of blood vessels, which can be measured by ultrasound of the heart,” Moreira said.

According to researchers, children with aneurysms are at the highest risk of future events.

“These are children who need significant observation and follow-up with multiple ultrasounds to see if this resolves, or if this is what they have for their rest of their lives. “Moreira said.

The researchers also found that nearly half of patients with MIS-C had underlying disease, and half of them were obese or overweight.

“In general, obese patients will have worse results, both in adults and children,” said Moreira.

The researchers found that the inflammatory markers of MIS-C were much more aberrant when compared to the original Covid-19 infection.

They gave an example of this abnormality and said that troponin, a molecular marker used to diagnose heart attacks in adults, was 50 times higher than normal levels in children with MIS-C.

“Evidence suggests that children with MIS-C have tremendous inflammation and potential tissue damage to their hearts, and we need to understand these effects to understand what their effects might be in the long run. You need to track your child carefully.