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Researchers use magnetic fields and hydrogels to grow new cartilage with incredible breakthroughs — RT World News
By combining magnetic fields and hydrogels, a team of researchers produced artificial cartilage using non-invasive methods that could revolutionize regenerative medicine.
Scientists at the University of Pennsylvania’s Perelman School of Medicine have demonstrated new ways to reconstruct complex body tissues that can significantly reduce the time to recover from common injuries, such as cartilage degeneration of important joints throughout the body.
Instead of the synthetic or biological materials commonly used for these types of injuries, a team led by Robert Mack, director of the McKay Institute and professor of orthopedics and biotechnology, has a team of ferrofluids and three dimensions. A combination of hydrogel solutions was used. It may match a particular nuance of an injury in the body.
In this way, cells and other objects involved in the treatment of a particular injury can be rearranged as needed and non-invasive, non-destructive processes can be used to mimic naturally occurring tissues. I will.
Researchers have avoided adding magnetic particles to the damaged cells themselves, citing undesired long-term effects, but instead opting for a non-invasive approach that “magnetizes” the environment around the cells. Did.
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In these types of injuries, often referred to as “soft tissue injuries,” the injuries are often not catastrophic and are confined to one or two areas, usually forming holes in the membrane.
Common modifications to the destruction of tissues such as cartilage work much like repairing roads and homes, filling holes with synthetic material. However, because such materials are non-organic, they tend to wear over time and can cause unwanted side effects.
In addition, the more complex the initial structure, the harder it is to find a suitable alternative to fill the gap while performing much the same function. Especially for cartilage, the surface is densely packed with cells, and the number of cells is much smaller when approaching the attached bone. In other words, synthetic alternatives need to be designed fairly finely.
The team’s hydrogel solution (and the medicines floating in it) is poured into the damaged area and then exposed to UV light to lock it in place. The magnetic solution then slowly diffuses out of the body over time.
The team has succeeded in reproducing the articular cartilage in important joints of the human body such as the knees and elbows, which are the main causes of injury for professional athletes. “”By immobilizing cells and other drug delivery agents in place through magnetic patterning, tissue can be initiated in the proper orbit and better implants for cartilage repair can be produced.“Mc said.
So far, the study has been conducted in a laboratory “in vitro” setting, but it shows the latest steps towards more advanced regenerative medicine technology without the need for multiple expensive and invasive surgeries. I will.
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