Health
Kenya launches Covid-19 vaccine trial-KBC
Kenya participates in a global effort to find an effective COVID-19 vaccine, with the launch of a trial aimed at assessing the efficacy of ChAdOx1 nCoV-19, a leading COVID-19 vaccine candidate. did.
The trial team vaccinated the first volunteers after receiving the required regulatory and ethical approvals from the Ministry of Health and the Kilifi County Government.
The study will be held in the Kilifi-based KEMRI-Welcome Trust research program. This is a long-standing collaboration between KEMRI, Oxford University and Wellcome Trust in the United Kingdom.
The ChAdOx1 nCoV-19 vaccine was developed by the University of Oxford in partnership with AstraZeneca and is currently being evaluated in several countries, including the United Kingdom, South Africa and Brazil.
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Kenyan Volunteer Performance
The trial in Kenya will initially involve 40 front-line workers in Kilifi County. Once the vaccine is confirmed to be safe, an additional 360 volunteers will be recruited to extend the trial to Mombasa County.
After vaccination, vaccine trial volunteers will be monitored for 12 months to assess their health status, vaccine side effects, and how the body develops immunity in response to the vaccine.
ChAdOx1 nCoV-19 was created by incorporating the genetic material of the SARS-CoV-2 virus into the ChAdOx1 adenovirus vaccine platform. The ChAdOx1 adenovirus vaccine platform has a well-established track record in its ability to safely elicit a human immune response when used in other diseases.
This has shown that the clinical development of ChAdOx1 nCoV-19 has progressed rapidly, with over 10,000 volunteers vaccinated in clinical trial facilities around the world and the vaccine tolerated well.
“Vaccines that work in one population do not necessarily work in all populations. This is the case with vaccines against malaria, rotavirus, and Ebola. Kenyans succeeded in the ChAdOx1nCoV-19 vaccine. It is important to evaluate its performance among Kenyan volunteers in order to be able to benefit from it, “the institute said in a statement.
KEMRI is interested in evaluating vaccines in Kenya, leveraging the institute’s established capabilities in conducting clinical trials in Africa and its long-standing collaboration with the University of Oxford.
The institute has been involved in the development of preclinical vaccines, initial trials in humans, and early and late evaluation of vaccine candidates for malaria, Ebola, Shigera, yellow fever, and pneumonia.
This study plans to evaluate whether the vaccine is safe and effective and elicits a good immune response among Kenyan adults over the age of 18.
The COVID-19 pandemic has an overwhelming impact on healthcare systems and economies around the world, and vaccines can help reduce these burdens.
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