Health
How does the Pfizer Covid Vaccine work?
Spike proteins from other coronaviruses have previously been used to develop vaccines for diseases such as Middle East Respiratory Syndrome (Mers) and Severe Acute Respiratory Syndrome (Sars).
The Covid “mRNA” vaccine is given to the muscles of the upper arm. When instructions (mRNA) enter the muscle cells, the cells use them to make spike proteins. After the proteins are made, the cells break down the instructions and remove them. The cell then displays the protein on its own surface.
Our immune system recognizes that proteins do not belong to it, builds an immune response and begins to make antibodies, as it does in real infections. When the vaccine is removed from the body, the cells return to normal operation.
These types of vaccines do not use live viruses that cause Covid and do not interact with DNA. The vaccine is degraded immediately after the cells have finished using the instructions without the mRNA entering the cell’s nucleus.
Dr. Zoltan Kish, Research Associate at the Future Vaccine Manufacturing Hub at Imperial College London, said: “This is the first mRNA vaccine approved and this technology is a vaccine against currently unknown viral pathogens.
“The current Covid-19 pandemic still has major manufacturing, distribution and management challenges, but MHRA. [Medicines and Healthcare products Regulatory Agency] Approval of the Pfizer / BioNTech vaccine is a major step towards overcoming this pandemic. “
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