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British women with breast cancer may be eligible for medicines to buy “precious” time | Breast Cancer

British women with breast cancer may be eligible for medicines to buy “precious” time | Breast Cancer

 


Women with advanced breast cancer England After a U-turn with the drug Watchdog, you can benefit from a new type of immunotherapy with the NHS.

National Institute health and Care Excellence (Nice) overturned Keytruda’s (pembrolizumab) refusal, stating that British women can take medicine in combination with chemotherapy.

medicine It can be used by patients with refractory secondary triple-negative breast cancer. Its purpose is to slow the progression of the disease and buy “precious” extra time for women.

Delyth Brest CEO Morgan cancer Now, he said the move was “absolutely great news” for patients with this illness. The median overall survival is 23 months with the new immunotherapy compared to 16.1 months with chemotherapy alone.

“Following Nice’s worrisome provisional rejection earlier this year, the reversal of this decision brings valuable additional time before the disease progresses, spending time living with loved ones, and important things. Brings hope to qualified women who can bring more months to do, most for them, “she said.

Keytruda is used for chemotherapy in women with triple-negative breast cancer whose tumor expresses PD-L1 and has a total positive score of 10 or higher. They may also not be receiving chemotherapy for progressive disease and will be treated if surgery is not performed. It is possible to remove the tumor.

Nice said after a previous rejection, the manufacturer’s MSD suggested that drug combinations should be restricted to people whose tumors express PD-L1 at CPS of 10 or higher. This helps the patient’s own immune cells attack the cancer.

Helen Knight, Interim Director of Drug Evaluation in Nice, said: Those who did not have access to atezolizumab, another immunotherapy recommended by Nice, gained important new options to help them live longer and spend more valuable time with their loved ones.

“Therefore, we recommend a smaller population than approved for pembrolizumab, which means that the maximum number of patients with advanced triple-negative breast cancer is currently receiving effective treatment. . “

Morgan said she hopes that women with advanced breast cancer will soon be able to benefit from more options. “Despite this positive news, she desperately advances the nice assessment of Trodelvy, another potentially life-prolonging drug for certain people with secondary breast cancer that was tentatively rejected in April. Must see in. “

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Separately, in the current Breast Cancer Survey, 1,007 women with breast cancer say that 44% say that breast cancer has a negative effect on body image and 25% say they have the same sense of identity.

Overall, 37% say the diagnosis worsens their mental health and self-esteem.

Sources

1/ https://Google.com/

2/ https://www.theguardian.com/society/2022/may/25/women-in-england-with-breast-cancer-to-qualify-for-drug-that-buys-precious-extra-time-keytruda

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