A Los Angeles County resident with a severely weakened immune system has died of monkeypox. Los Angeles Public Health Department reported (opens in new tab) Monday (September 12th). The U.S. Centers for Disease Control and Prevention (CDC) also evaluated the case and confirmed that the death was due to monkeypox infection, according to the Department of Health.
“The resident was hospitalized with severe immunocompromise,” said a health department statement.In general, immunocompromised people are at higher risk of severe illness monkeypox Children under 8 years of age, people with a history of eczema, and pregnant Or breastfeeding, Live Science previously reported.
“To protect confidentiality and privacy, no additional information regarding this incident will be released,” the statement continued. “Severely immunocompromised people who are suspected of having monkeypox are encouraged to seek medical care and treatment early and to remain in the care of a provider during the illness.”
Los Angeles resident death may mark first confirmed U.S. monkeypox death during ongoing outbreak. The Texas Department of Health Services reported (opens in new tab) A similar case of a severely immunocompromised individual who died after being diagnosed with monkeypox. But at the time, officials were investigating what role monkeypox played in that death. And he said as of September 12, authorities had yet to announce whether the deaths were due to monkeypox. The Los Angeles Times reported (opens in new tab).
Related: Should everyone get the monkeypox vaccine?
As of Monday, about 58,000 monkeypox cases had been reported worldwide, of which about 57,500 occurred in places where monkeypox had not historically spread. According to the CDC (opens in new tab)About 22,000 cases have been reported in the United States alone, 4,300 of which are in California. agency reported (opens in new tab).
At least 18 people worldwide have died from monkeypox, eight in places where monkeypox is not normally endemic and 10 in places where monkeypox is endemic. (It’s unclear if this death toll has been updated to reflect his LA resident’s death, but as of Tuesday (September 13), the death toll is not yet pointed out (opens in new tab) At the CDC’s main monkeypox landing page. )
monkeypox virus The virus causing the current outbreak, known as the clade II monkeypox virus, is generally less lethal than other monkeypox strains. Historically, clade II viruses (previously called the West African clade) killed 1% to 3.5% of those diagnosed with the disease, while clade I viruses (previously the Congo Basin clade) killed 6%. has a fatality rate of 10% from , Live Science previously reported.
People who die from monkeypox may be due to pulmonary distress. inflammation in the air sac of lung (bronchopneumonia) or inflammation brain develops as a result of infection (encephalitis), STAT report (opens in new tab)Other monkeypox deaths have been linked to secondary infections bacteria Infection and sepsis, a life-threatening immune response that causes widespread inflammation and organ damage.
So far, in the current outbreak, doctors have not determined whether everyone who died of monkeypox died from the same direct cause, such as lung disease or sepsis, STAT reports. This could become apparent if the data on each death were made public or described in research papers.
Originally published in Live Science.
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