Health
Existing asthma treatment turns out to be a 'game changer' for asthma and COPD attacks
A drug already used to treat severe asthma may help treat exacerbations of asthma and COPD, a British trial has found.
The monoclonal antibody benralizamab was found to be more effective than steroids when patients presented to the emergency department or emergency department with acute symptoms and elevated eosinophil counts.
Researchers at King's College London said their findings could be “transformative” in a field of medicine that has remained unchanged for 50 years.
In this trial, patients with asthma or COPD attacks were treated with benralizumab injections and a placebo tablet, standard care of 30 mg prednisolone per day for 5 days plus a placebo injection, or both benralizumab injections and steroids. randomly assigned to receive group.
After 28 days, patients receiving benralizumab were found to have improved cough, wheezing, shortness of breath, and sputum production.
After 90 days, the researchers reported that four times fewer people had failed treatment in the benralizumab group compared with prednisolone alone. lancet respiratory medicine.
The researchers also found that treatment with benralizumab “takes longer to fail,” meaning fewer visits to GPs and hospitals.
The quality of life of asthma and COPD patients also improved, the researchers added.
Almost three-quarters (74%) of patients who received standard-of-care prednisolone required further treatment within 90 days, which is in line with the poor performance currently seen with short-term steroid administration when treating eosinophilic exacerbations. The research team concluded that the findings highlight outcomes.
Benralizumab injections could be given in a general practitioner's office or emergency department, the researchers added.
New items will be released just like last week Joint NICE/BTS/SIGN guidelines for asthma management finally published.
Study leader Professor Mona Buffadel, director of the King's Lung Health Centre, said: “Benralizumab is a safe and effective drug that is already used to manage severe asthma.”
“We used this drug in a different way, at the point of exacerbation, to show that it is more effective than steroid tablets, the only treatment currently available.
She added that a major advance in this research was the discovery that targeted therapies could be effective in treating asthma and COPD attacks.
“Rather than giving everyone the same treatment and guessing what kind of treatment they need, it's much better to target the highest-risk patients with very targeted treatments with appropriate levels of inflammation. I found it to be excellent.”
Dr Samantha Walker, director of research and innovation at Asthma + Lung UK, said: “The discovery of a potential alternative to administering steroid tablets in the treatment of asthma attacks and COPD exacerbations is a great opportunity for people with lung disease. That's good news for us.”
“But the fact that this is the first new treatment for people suffering from asthma and COPD attacks in 50 years is frightening and shows how desperately underfunded lung health research is. ”
|
Sources 2/ https://www.pulsetoday.co.uk/news/clinical-areas/respiratory/existing-asthma-drug-found-to-be-game-changer-in-asthma-and-copd-attacks/ The mention sources can contact us to remove/changing this article |
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
to request, modification Contact us at Here or [email protected]
 |
 |
 |
