British scientists make 1 million potential COVID-19 vaccines before proof

LONDON (Reuters) -One million doses of COVID-19 vaccine potential being developed by British scientists has already been manufactured and even before trials proved to be valid 9 The team said Friday that it will be available by the month.

The Oxford University team’s product, called “ChAdOx1 nCoV-19,” is a type known as a recombinant viral vector vaccine, with at least 70 potential COVIDs under development by biotechnology and research teams around the world. -One of 19 candidate shots.

At least five of them are undergoing people’s preliminary testing.

Oxford scientists said Friday that they were recruiting volunteers for the early stages of their shots-Phase 1-human trials, and large production capacities were placed “at risk”. Told. This means that if your trial reveals that your shots aren’t working, you run the risk of spawning too many shots and rendering them useless.

“We’re starting to risk producing this vaccine. Not only on a small scale, we have a network of manufacturers in seven different locations around the world,” said Professor Jenner Institute at Oxford University. Director Adrian Hill University told reporters during an online briefing.

“The aim is to administer at least 1 million doses by September, when the results of the effect (test) can be expected.”

He said three of his manufacturing partners are in the United Kingdom, two in Europe, one in India and one in China.

Scientists said the initial manufacturing cost would be “tens of millions of pounds,” admitting the investment risk of advancing production before testing.

They did not provide details of the funding.

According to Reuters tally, more than 2.14 million people are reported infected with the new coronavirus worldwide, killing 143,744 people.

Hill’s team says it will start safety-checking the potential COVID-19 vaccine’s mid-stage efficacy in a matter of weeks in adults between the ages of 18 and 55. It was.

Later, the pilot group will be expanded to a senior group, with a final-stage trial conducted by approximately 5,000 volunteers at the end of summer.

Hill and his collaborators-including Oxford professor of vaccinology Sarah Gilbert-say that human testing of one shot of ChAdOx will show positive results in protection against COVID-19 infections. I’m very confident. ”

They acknowledged that many other research teams around the world are also working on potential vaccines, and the chances of complete success are only part.

“We can never be sure that these things will work,” Gilbert told the briefing. “In my opinion, this is very likely to work.”

Asked that a shot-if proven to work-may become widely available to the public, Hill says regulators grant the “urgent use approval” is the best scenario. What you can achieve within 6 weeks-Points that indicate whether the data is valid.

That could mean about six weeks from September when the team wants to get positive test data, he said.

Report by Kate Kerland. Edited by Andrew Kawthorne

Our criteria:Thomson Reuters Trust Principles.

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