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USask VIDO announces positive results for Phase 1 of COVAC-2

 


Saskatoon – Today, the University of Saskatchewan (USask) Vaccine Infectious Diseases Organization (VIDO) announces positive interim results from Phase 1 clinical trials of COVAC-2, a candidate for VIDO’s COVID-19 subsystem vaccine. did.

Interim data from a study led by the Canadian Center for Vaccination (CCfV) show that COVAC-2 is safe and well tolerated. The most common and common reaction reported was headache, and the most prominent local reaction was mild injection site pain. These reactions are common after most vaccinations.

Importantly, even the lowest vaccine dose tested significantly increased antibody levels in participants, including neutralizing antibodies to SARS-CoV-2. Neutralizing antibodies are associated with protection.

“The data continue to show the safety of the subunit vaccine COVAC-2,” said Dr. Volker Gerdts, director and CEO of VIDO. “We are encouraged by the vaccine’s ability to produce a significant immune response, even at the lowest doses tested.”

COVAC-2 is a protein subunit vaccine. Subunit vaccines contain purified viral proteins that are not infectious, and this technology has many advantages, including a history of safety and ease of storage and transportation. The vaccine is prescribed using Sepivac SWE ™, an adjuvant developed by Seppic and the Vaccine Formulation Institute (VFI). An adjuvant is an ingredient that improves the immune response of a vaccine.

Participants will continue to be recruited for clinical trials at Halifax’s CCfV, and a new clinical trial site will open in Saskatoon later this summer. If you are 18 years of age or older, have not been infected with COVID-19, have not been vaccinated with a licensed COVID-19 vaccine, and wish to volunteer, the Clinical Trials Support Unit ([email protected] or 306-978) Please contact -8300). Saskatchewan), or email [email protected] (Nova Scotia).

“We are pleased to partner with VIDO to open this research site in Saskatoon,” said Principal Investigator Dr. Stephen Sanche. “I am grateful that the people of Saskatchewan have already shown interest and are looking for more volunteers to complete the study.”

VIDO’s COVID-19 vaccine development is supported by the Government of Canada and the Government of Saskatchewan. It is run by the Government of Saskatchewan for Innovation Saskatchewan and the Canadian Innovation Foundation through a Key Science Initiative Fund.

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