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Research finds that licorice extract may treat COVID-19

 


Key Point

  • Extract from Chinese licorice is advertised by Chinese as a cure for COVID-19
  • An extract called liquiritin has been shown to prevent rapid replication of SARS-CoV-2 in monkey cells
  • The claim was based on a non-peer reviewed study currently submitted for comment.

Traditional Chinese Medicine (TCM) provides the world with an extract from flowering licorice (Glycyrrhiza uralensis) as a potential cure for COVID-19.

The root extract is a flavonoid called “liquiritin.” In a first non-peer-reviewed study by Beijing researchers, liquiritin blocks rapid replication of COVID-19-causing virus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) in monkey cells. Claims to have been shown.

In TCM, liquiritin is commonly processed and sold as herbal licorice tablets and is also widely used as a sweetener. It is also commonly used for gastrointestinal and respiratory problems.

“Riviritin is recommended as a competitive candidate for treating Covid-19.” The team said Preprinted paper for the bioRxiv website of Peking University and the Academy of Military Sciences.

In this study, artificial intelligence (AI) technology was used to accelerate the research process. We have found that AI predicts the efficacy of liquiritin and significantly inhibits Sars-CoV-2 replication in Vero cells, a cell line developed from monkeys.

The team also tested liquiritin in mice for 7 days. They observed liquiritin “not showing toxicity or side effects in two independent experiments.”

“In summary, we propose that riboquitin should be evaluated in human patients with Covid-19,” the study said.

They also suggested that liquiritin may have a “widespread and potent antiviral function against other viral pathogens” such as hepatitis B and HIV.

It is striking to learn that TCM was given to over 90% of Chinese COVID-19 patients as part of their treatment. However, there are no statistics or evidences demonstrating the effectiveness of TCM against COVID-19. This is a result of Western doctors being very skeptical of these claims.

Liquiritin, a component of licorice, has been studied in a rat model for its effect in chronic variable stress-induced depression. Studies found Antidepressant-like effect. This may be related to the prevention of the observed oxidative stress. In another study, liquiritin resulted in reduced pigmentation in a double-blind, contrasting, face-segmented study of 20 women with melasma.

In the West, licorice is usually associated with candy licorice. Licorice candy is usually colored black with licorice root extract. The essential ingredients of black licorice candy are licorice extract, sugar and binder.

Black licorice Licorice contains a licorice root-derived sweetener, glycyrrhizin, which can specifically target and reduce potassium levels in the body. This photo depicts a fruit and licorice gum by German sweets maker Haribo on February 17, 2017 in Paris. Photo: Getty Images / JOEL SAGET

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