Researchers found that remdecivir, a treatment for coronavirus, reduced the virus in monkeys

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Coronavirus Processing Rem decivil The researchers note that delaying the progression of COVID-19 and preventing lung disease in macaques supports early use of antiviral drugs in human patients.

A study conducted by Emmy DeWitt, who is in charge of the Molecular Pathogenesis Unit at the National Institutes of Health, and her colleagues is published in the journal. Nature..

“Early treatment with the antiviral drug lemdecivir has been shown to reduce viral load and prevent lung disease in macaques infected with SARS-CoV-2,” the researchers wrote in an email to Fox News. Explained in. “The findings support the early use of lemdecivir therapy to prevent progression to pneumonia in COVID-19 patients.”

Rendescivir: What You Should Know About Potential Coronavirus Treatment

Gilead’s science remdesivir has recently received extensive attention with the FDA Authorization Emergency use of drugs to treat patients with coronavirus. Antiviral drugs Shortening Recovery time for COVID-19 patients, according to a human study recently cited by the US government.

A small flock of rhesus monkeys-a photo of the file.
(IStock)

In the Dwitt study, researchers used a model of SARS-CoV-2 infection to investigate the effects of lemdesibir treatment in rhesus monkeys. “Two sets of six monkeys were vaccinated with SARS-CoV-2. One group was treated with lemdesibir 12 hours later (near the peak of viral replication in the lung), and these macaques were 6 days post vaccination. I received treatment every 24 hours,” the researchers explained in a statement. “In contrast to the control group, monkeys receiving lemdecivir showed no signs of respiratory disease and reduced damage to the lungs.”

Scientists say that lower respiratory tract viral load was also reduced in treated animals. “Twelve hours after the first dose, the lower respiratory tract of macaques treated with lemdesibir had viral levels reduced by about 100-fold,” they explain. “Infectious virus was not detected in the treatment group 3 days after the initial infection, but was still detected in 4 out of 6 control animals.”

Developer Gilead says coronavir treatment rendecivir reaches patients this week

However, despite a reduction in viral load in the lower respiratory tract of animals, researchers did not observe a reduction in viral shedding. This indicates that clinical improvement may not be comparable to lack of infectivity, they said.

Antiviral drugs were previously used to treat patients with Ebola. Experts warn that people should not take drugs unless they are prescribed by a doctor.

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According to data from Johns Hopkins University, as of Tuesday morning, more than 7.1 million cases of coronavirus cases were diagnosed worldwide, including 1.9 million cases in the United States. The disease accounts for at least 407,009 deaths worldwide and at least 111,007 deaths in the United States.

Fox News’s Jonathan Serrie, Chris Ciaccia, and AP contributed to this article. Follow James Rogers on Twitter @jamesjrogers

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