Health
Why do we catch colds in winter?blame the nose
December 6, 2022 – New research finally provides evidence why we’re more likely to catch the virus in the winter.
The results may seem obvious: because it’s colder.
“There has never been a compelling reason for a very clear increase in viral infectivity in cold weather,” said Benjamin Brier, M.D., Ph.D., a researcher at Harvard Medical School. news release“This is the first quantitative and biologically plausible explanation developed.”
This study evaluated a known immune response in the nose known as ‘extracellular vesicle release’. This is when your nose releases a spray that swarms, binds, and kills the bacteria you inhale.
“It’s like if you kick a hornet’s nest, all the hornets will come out and attack,” Brier said. “The nose detects these pathogens and releases a swarm of extracellular vesicles.”
In this study, volunteer nose samples were evaluated at normal and 9 F below body temperature in the lab to simulate the temperature difference between indoors and outdoors in winter. At low temperatures, the spray was sparse.
The study was published this week Journal of Allergy and Clinical Immunology.
Mansur Amiji, PharmD, PhD, a fellow researcher at Northeastern University, said the research could help prevent SARS-CoV-CoV, the virus that causes COVID-19, by leading to new ways to prevent viral infections such as: said it may be related to stopping the spread of 2. Development of “artificial virus sponge”.
Scientists not involved in the study said the discovery was groundbreaking, but it also had limitations.
“This is the first time we have a biological and molecular explanation for one factor in the innate immune response that seems to be limited by cold temperatures,” said rhinologist Zara Patel, M.D., Ph.D. CNN“It’s important to remember that these are in vitro studies, meaning that we’re using human tissue in the lab to study this immune response, but it’s not done in someone’s actual nose.” The results of in vitro studies are often, but not always, confirmed in vivo.”
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