Health

COVID-19 spike protein can cause leaky blood vessels, possible organ failure

Berkeley (CBS SF/BCN) – A study by researchers at the University of California, Berkeley, found that the COVID-19 spike protein may help blood vessels secrete fluid into the body, leading to respiratory failure and other conditions. can lead to serious health consequences.

The study, published Friday in the journal Nature Communications, found that the spike protein in COVID viral particles can damage blood vessel walls throughout the body, causing a condition known as vascular leakage.

As a result, intravascularly transported plasma and other fluids can lead to lung and heart damage, which is common in severe COVID cases.

Blocking the protein’s damage to blood vessels may help prevent some of the virus’ most serious symptoms and consequences, researchers say.

“Given all the different variants that have emerged and the difficulty of preventing infection from each one individually, it would be a good idea to block the infection completely,” said Scott Biering, a postdoctoral researcher at the University of California, Berkeley. In addition, it may be beneficial to focus on these etiological triggers.” First author of the study.

The spike protein can function similarly to the dengue virus protein NS1, researchers said. and can lead to organ failure.

The researchers also noted that the spike protein does not cause symptoms by itself, but instead works together with the viral COVID infection to cause severe illness.

“We have identified this protein secreted by dengue virus-infected cells that can disrupt the internal barrier even in the absence of the virus,” said a professor at the University of California, Berkeley.

“So I wondered if a SARS-CoV-2 protein like Spike could do something similar,” Harris said.

The results and future analyzes of this study may ultimately help medical and scientific researchers develop new treatments for COVID that can specifically prevent serious illness.

“We have a better vaccine now, but we don’t know how the virus will mutate in the future.” It could help us develop an arsenal of new drugs so that we can.”

The full study can be found at: Nature.com.

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2/ https://www.cbsnews.com/sanfrancisco/news/covid-19-spike-protein-could-cause-blood-vessel-leaks-possible-organ-failure/

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