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Study: Past COVID-19 infection may protect against cold

Study: Past COVID-19 infection may protect against cold

 


Cardiac arrest
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Patients who received one or more doses of the COVID-19 vaccine after an acute coronary syndrome (ACS) had similar rates of all-cause death, heart attack, stroke, emergency coronary revascularization, major cardiovascular events, chest pain, heart failure and hospitalization for respiratory infections as unvaccinated patients, a secondary study found. analysis of a randomized clinical trial.

This study JAMA Network Open.

No reduction in MACE

An international team led by researchers from the Israel Albert Einstein Hospital in São Paulo, Brazil, analyzed the results of influenza vaccination trials to prevent cardiovascular events after acute coronary syndrome.

The study evaluated the efficacy of influenza vaccination after ACS from July 2019 to November 2020, and in a secondary analysis, the incidence of cardiopulmonary events in patients who received at least one dose of COVID-19 vaccination in Brazil was compared with unvaccinated participants. In the secondary analysis, patients were not randomly assigned to a COVID vaccine.

In a secondary analysis of this randomized clinical trial, patients who received at least one dose of COVID-19 vaccination after ACS had a similar primary composite endpoint and incidence of MACE compared with unvaccinated patients.

Of the 1,801 patients (median age 56.7 years, 30.3% female), 16.2% had a history of heart attack and 35.7% were current smokers. In total, 1,665 patients had no cardiopulmonary events during the first 90 days, of which 50.2% had received at least one dose of COVID-19 vaccine. Most patients (63.9%) had received at least one dose of the Oxford/AstraZeneca vaccine during the follow-up period.

In unvaccinated individuals, the 90-day event-free follow-up rates per 100 patient-years for all-cause death, heart attack, stroke, emergency coronary revascularization, major cardiovascular events, chest pain, heart failure, and hospitalization for respiratory infection were 4.81 in vaccinated individuals compared with 9.37 in unvaccinated individuals (adjusted hazard ratio[HR]0.01). [aHR]0.41).

Vaccination is mace (aHR, 0.32), all-cause mortality (aHR, 0.29), or cardiovascular death (aHR, 0.42).

“In this secondary analysis of a randomized clinical trial, patients who received at least one dose of COVID-19 vaccination after ACS had a similar primary composite endpoint and incidence of MACE compared with unvaccinated patients,” the researchers wrote. “However, retrospective studies have demonstrated a short-term reduction in MACE risk after COVID-19 vaccination.”

Sources

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2/ https://www.cidrap.umn.edu/covid-19/study-previous-covid-19-infection-may-protect-against-common-colds

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