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Robust immune response, covaxin maker after monkey research

 


Kovacin: Bharat Biotech Announces Results of Vaccine Candidates Given to Animals in Trials

New Delhi:

Bharat Biotech, who develops the coronavirus vaccine COVAXIN in the latest report, states that animal studies have shown that vaccine candidates help develop a strong immune response against highly infectious coronavirus.

“In summary, vaccine candidates have been found to produce a strong immune response, thus preventing infection and disease in primates exposed to high doses of the live SARS-CoV-2 virus,” Bharat Biotech said. Posted on the website.

“These results demonstrate a protective effect in the viral challenge model,” the company tweeted.

It said that 20 rhesus monkeys divided into four groups were given vaccine candidates.

“One group received placebo and three groups were immunized with three different vaccine candidates at 0 and 14 days. All monkeys were exposed to viral attack 14 days after the second dose.” Bharat Biotech said.

“The results showed a protective effect, increased SARS-CoV-2 specific IgG and neutralizing antibodies, and reduced viral replication in the nasal cavity, throat, and lung tissue of monkeys. Unlike the placebo group, 2 No adverse events were seen in the animals vaccinated with the rounds. “

Bharat Biotech began human experimentation in July after approval from the national drug regulatory agency.

COVAXIN was scheduled to hit the market by August 15, but government officials later told Parliament’s Standing Committee that such drugs would not be possible until at least next year.

Worldwide, more than 100 vaccines have been developed and tested to thwart the COVID-19 pandemic. This killed hundreds of thousands and destroyed the world economy.

Oxford University’s potential COVID-19 vaccine, approved by AstraZeneca, is probably the most promising candidate in the world and the most advanced in terms of development. However, it was suspended after one of the subjects in the study showed an adverse reaction.

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