Health
Lung damage found in COVID dead may shed light on “long COVID”-study
London (Reuters)-Lung studies of people who died of COVID-19 most often found persistent and widespread lung damage, behind what is known as the “long COVID” that patients suffer. Symptoms that are ongoing for several months that may help doctors understand.
Scientists leading the study said they also discovered some unique features of SARS-CoV-2, the virus that causes COVID-19. This may explain why such harm can be done.
Professor Mauro Jacka of King’s College said: London co-led the work.
The research team analyzed tissue samples from the lungs, heart, liver, and kidneys of 41 patients who died of COVID-19 at the University Hospital of Trieste, Italy, between February and April 2020.
In a telephone interview, Jacka said his research team showed no obvious signs of viral infection or long-term inflammation in other organs, but healthy tissue was “almost completely replaced by scars” and “lungs.” He said he had found “a very large destruction of the structure.” Organization “.
“Major” damage
“It’s very likely that one of the reasons for long COVID cases is due to the massive destruction of the lungs (tissues),” he told Reuters. “Even if someone recovers from COVID, the damage done can be enormous.”
Increasing evidence from around the world could allow a small number of people infected with COVID-19 to recover from the initial infection to experience a variety of ongoing symptoms such as fatigue, brain fog, and shortness of breath. It has been suggested that there is sex. This condition is often referred to as “long COVID”.
Almost 90% of 41 patients had some characteristics specific to COVID-19 compared to other forms of pneumonia, Jacka said.
One was that the patient had extensive blood clots in the pulmonary arteries and veins. The other was that some lung cells were abnormally large and had many nuclei. This is the result of different cells fusing into a single large cell in a process known as syncytium.
A study published in the journal Lancete BioMedicine also found that the virus itself is still present in many types of cells.
“The presence of these infected cells can cause the major structural changes observed in the lungs, which can last for weeks or months and can ultimately explain the” long COVID “. There is sex, “said Giacca.
Report by Kate Keland, edited by Gareth Jones
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