Studies have found that breakthroughs in LSD may enable the treatment of autism and social anxiety.

Wednesday, January 27, 2021 10:45 GMT Lysergic acid diethylamide (LSD) became a popular psychedelic drug in the 1960s and is once again popular. Some young experts claim to use microdoses to increase creativity.Despite rigorous analysis and experimentation, including the CIA's illegal MKUltra project in the 1950s, scientists have never been able to determine the mechanism by which LSD acts on the brain.Researchers at McGill University in Canada have discovered that LSD activates serotonin 5-HT2A and AMPHA receptors in the brain, both of which combine to promote social interaction.In their study, published in the journal PNAS, scientists administered low-dose LSD to mice over a 7-day period and found that it resulted in an observable increase in their sociability.Although mouse behavior is not directly equivalent to human behavior, researchers pointed out that it closely resembles empathy and social behavior, but the main results identify the underlying mechanism of behavioral effects. It was that."The fact that LSDs bind to 5-HT2A receptors has long been known," said report co-author Professor Nahum Sonenberg of the Department of Biochemistry at McGill University."The novelty of this study is that we have identified that the prosocial effects of LSD activate 5-HT2 receptors, which in turn activate the excitatory synapses of AMPA receptors and the protein complex mTORC1. . "A previous study by Professor Sonnenberg has demonstrated that these brain pathways are dysregulated in psychiatric disorders with social defects such as autism spectrum disorders.The next step for researchers is to test LSD in mutant mice that exhibit behavioral disorders similar to human pathology, such as autism spectrum disorders and social anxiety disorders.According to McGill University, "finally whether microdosing of LSD or some novel derivatives could have similar effects in humans, and whether it could also be a viable and safe treatment option. Is to investigate. ""Social interaction is a fundamental feature of human behavior," added co-author, Professor of Psychiatry at McGill University and Dr. Gabriella Gobi, a psychiatrist at McGill University Health Center."These hallucinogens can enhance sociality at low doses, better understand the pharmacology and neurobiology of social behavior, and ultimately provide new and safer drugs for mental illness. It may help you develop and discover. " '); //-> Pictures Credit

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Studies have found that breakthroughs in LSD may enable the treatment of autism and social anxiety.

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Studies have found that breakthroughs in LSD may enable the treatment of autism and social anxiety.

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