Health
How Rani Therapeutics Robotic Pills Can Transform Subcutaneous Injection Treatment
New automatic injection pills may soon replace subcutaneous injection treatment.
Ideas for this So-called robot pill It came out of a research project about 8 years ago InCube Lab — A life science lab run by Mir Imran, Chairman and CEO of Rani Therapeutics, who holds a degree in electrical and biomedical engineering from Rutgers University. Life Science Innovation celebrity Imran has founded more than 20 medical device companies to help develop the world’s first implantable cardioverter-defibrillator.
In working on the technology behind San Jose-based Rani Therapeutics, Imran and his team reduce some of the painful side effects of subcutaneous (or subskin) injections while improving the effectiveness of treatment. I wanted to find a way. “The technology itself started with a very simple treatise,” Imran said in an interview. “We wondered why we couldn’t make a pill containing the biological drug you swallowed, and when it reaches the intestines, it deforms itself and provides a painless injection. To do.”
Rani Therapeutics’ approach is based on the unique properties of the gastrointestinal tract. The tablet injection mechanism is surrounded by a pH-sensitive coating that dissolves as the capsule moves from the patient’s stomach to the small intestine. This ensures that the pill begins to inject the drug in the right place at the right time. Once there, the reactants mix to produce carbon dioxide. Carbon dioxide inflates a small balloon, creating a pressure differential that helps inject a drug-filled needle into the intestinal wall. “So it’s a really timely sequence of events that will bring about this needle delivery,” Imran said.
Despite the slightly mechanical procedure, the pill itself does not contain metal or springs, which reduces the likelihood of an inflammatory reaction in the body. Needles and other components are made of injectable grade polymers instead, and Imran states that it is also used in other medical devices. When injected into the upper part of the small intestine, there is little risk of infection because the acid in the stomach and the spread of bile from the liver prevent the growth of bacteria.
One of Imran’s priorities for pills was to eliminate the painful side effects of subcutaneous injections. “It doesn’t make sense to replace them with another painful injection,” he said. “But your intestines don’t have the pain sensors that your skin has, so biology was on our side.” In addition, an injection into the highly angiogenic wall of the small intestine. When administered, it can actually be treated more efficiently than when applied via a subcutaneous injection, which usually deposits the treatment in adipose tissue.
Imran and his team plan to use the pill for a variety of indications, including growth hormone disorder acromegaly, diabetes, and osteoporosis. In January 2020, octreotide, a treatment for acromegaly, Demonstrate both safety and sustainable bioavailability In primary clinical trials. They hope to pursue future clinical trials for other indications, but initially chose to prioritize acromegaly because of its established treatment, but “very painful injections. “Imran said.
Rani Therapeutics at the end of last year Raise $ 69 Million New Funds We support further development and testing of the platform. “This will fund us in the next few years,” Imran said. “Our approach to business is to make technology extremely robust and manufacturable.”
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
Pictures Credit
to request, modification Contact us at Here or [email protected]
 |
 |
 |
