Health
Researchers at McMaster say trials suggest that common drugs reduce the risk of heart attack and stroke by half-Hamilton
recently study Based on data from a pair of Hamilton-based researchers, it suggests that common daily drug combinations can reduce the risk of heart attack and stroke in half.
In a randomized trial, researchers found that a mixture of drugs containing aspirin, blood pressure therapy, and statins (lipid-lowering drugs) had a 53% risk of heart attack, a 51% risk of stroke, and a risk of cardiovascular death. Forty-nine percent of people found to reduce their blood pressure provide maximum protection to people over the age of 65.
“This is one of the most important discoveries in cardiovascular disease in 30 years and the number one murderer in the world,” said McMaster’s medical professor, Hamilton Health Sciences (HHS) chief scientist and cardiac. Says Salim Yusuf, a specialist. ..
“The widespread use of this simple treatment can prevent 5 to 10 million individuals who experience a stroke, heart attack, or death from these conditions each year.”
Philip Joseph, an associate professor of medicine at McMaster University and an HHS cardiologist, draws conclusions from three randomized trials of more than 18,000 men and women from 26 countries. I was a principal investigator.
Subjects with an average age of 63 years and no previous cardiovascular disease (CVD) were followed for 5 years throughout the campaign. 2016, 2019, When 2020 We evaluated the efficacy of “Polypill” — a fixed dose combined with a single dose.
Both Youssef and Joseph have been leaders in many recent studies on CVD risk factors around the world for the past two decades.
In 2019, more than 70% of CVD cases were associated with 14 modifiable risk factors, including behavioral factors such as hypertension, abdominal obesity, smoking, diet, physical activity, alcohol consumption, and salt intake. Contributed to the report that I found.
“It’s clear that the majority of cardiovascular cases and deaths are explained by a small number of common and modifiable risk factors, which may improve,” Joseph said in 2019 on CVD risk. I mentioned it after publishing my paper.
“It’s worth noting that some of the most influential risk factors in the past, such as physical fitness, poor education, and indoor and outdoor air pollution, have proved to be more important than the other factors we have focused on. As obesity and salt. “
The concept of polypills was first proposed as a strategy 20 years ago and facilitated recent research developed in 2001 after a workshop with the World Health Organization (WHO) in London, England.
According to Yusuf, the development of polypills could reduce CVD by 65-70% worldwide and reduce the total cost of various drugs.
“Polypills are generic and have low manufacturing costs, which makes them available to people at a reasonable cost,” says Yusuf.
© 2021 Global News, a division of Corus Entertainment Inc.
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