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Species Crossing: The Growing Threat of H5N1 Bird Flu in the United States | Transmission

Species Crossing: The Growing Threat of H5N1 Bird Flu in the United States | Transmission

 


new york academy of sciences

CDC recently confirmed a human case of HPAI A(H5N1) in Texas. Renowned epidemiologist Shira Maddad and renowned virologist Jason Kindrachuk offer tips to farmers, animal handlers and the general public on how to avoid contracting and spreading this type of avian influenza. .

Avian influenza H5N1, commonly known as avian influenza, is a viral infection that affects both domestic and wild birds, as well as a wide range of other animals. It was first identified that 1996H5N1 has recently re-emerged in a prominent panzoan form, particularly clade 2.3.4.4.b, affecting a wide range of wild and domestic animals, including: 200 mammal species.

Worryingly, this includes confirmed infections of a number of species not previously known to be susceptible to H5N1, including marine mammals, as well as agricultural mammals, including: It is included. cow and goat. Rapid geographic expansion to all continents except Australia is also a concern. This remarkable interspecies spread is particularly concerning because of the potential for serious illness and death in humans, as well as economic and food security implications. This includes both the agricultural industry as well as communities that rely on wild game as a food source.

Confirmed cases in Texas

In March, CDC confirmed a human case of HPAI A(H5N1) in Texas associated with contact with an infected dairy cow, marking the first documented case of suspected mammal-to-human transmission in the United States since 2022. This is the second human case. Although human infection is rare and no sustained human-to-human transmission has been reported in the United States, this event suggests that her H5N1 may have been transmitted to infected animals or individuals in close proximity to contaminated environments. It highlights the real risks posed.

It should be noted that A single mutation previously found to be associated with adaptation to mammalian hosts was identified in the genome sequence of a virus isolated from a recent U.S. case. (PB2 E627K). However, while this indicates the need for continued monitoring and analysis of the H5N1 genome sequence, there is currently no evidence to suggest changes in human-to-human transmission of the virus or increased antiviral resistance. The CDC currently believes the risk to the broader U.S. population is low. Nevertheless, people who have unprotected long-term exposure to infected birds or animals or contaminated areas are at increased risk of contracting the virus.

The table below provides an overview Recommendation Precautions aimed at reducing the likelihood of H5N1 infection, both for the general population and for people whose work or recreational activities put them at increased risk.

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2/ https://www.unmc.edu/healthsecurity/transmission/2024/04/17/crossing-species-the-rising-threat-of-h5n1-bird-flu-in-the-u-s/

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