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New study reveals high risk of deep vein thrombosis in patients suffering from Covid-19

 


Researchers have found that inpatients suffering from Covid-19 are at increased risk of deep vein thrombosis or venous thromboembolism (VTE) and pulmonary embolism.

Deep vein thrombosis is a serious condition that occurs when a blood clot forms in a vein deep inside the body. This condition is serious because the blood clots can loosen and stay in the lungs.


The VTE risk for inpatients in general wards is 5-11%, but the risk of developing deep vein thrombosis or pulmonary embolism in critically ill patients is 18-28%, the study published in the journal Research and Practice in Thrombosis. It has been. And hemostasis was reported.

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“From the beginning of the Covid-19 pandemic, the study reported an increase in thrombosis and pulmonary embolism in Covid-19 patients,” said Cihan Ay, a research author at the Vienna Medical University in Austria.

“Our study now provides a better understanding of the underlying risks and therefore supports individual treatment decisions based on accurate risk assessments of different patient groups,” Ay added.

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For the findings, the research team evaluated a total of 5,951 studies published in the field of VTE in Covid-19. Of these, 86 studies were found to be eligible for inclusion, and the incidence of thrombosis and pulmonary embolism in Covid-19 patients was reported. After excluding additional studies due to the potential risk of bias in a structured assessment, 66 studies (28,173 patients) performed a meta-analysis to provide a solid estimate of the risk of VTE in Covid-19. I found that I was eligible to provide it.

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The main findings are as follows. Despite having a rigorous thrombosis prevention regimen in most studies, the overall VTE risk for inpatients with Covid-19 is 14%. In addition, high VTE rate heterogeneity was found among different patient subgroups. This rate was highest among patients admitted to the intensive care unit, with 23% of patients suffering from VTE.

Patients admitted to the general ward suffered from VTE in 8% of cases. These findings underscore the high risk of VTE in patients with Covid-19. In addition, the authors focused specifically on estimating the risk of potentially life-threatening pulmonary embolism. “This risk is significantly higher than other comparable serious medical illnesses and ranges from 10 to 18 percent in Covid-19 patients who require intensive care.

In addition, exploratory analysis revealed that patients who developed deep vein thrombosis or pulmonary embolism during hospitalization showed significantly higher D-dimer levels at admission. This is a test parameter that indicates the activation of the coagulation system. These findings underscore the strong impact of Covid-19 on the blood coagulation system.

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