Health
New all-in-one vaccine could prove effective against all coronaviruses
A team of scientists from one of the world's leading universities has developed a new all-in-one vaccine that is expected to be able to protect humans from a wide range of coronaviruses, including those that have not yet emerged.
The study, published Monday in Nature Nanotechnology, is based on a new approach to vaccine development called “proactive vaccinology,” in which scientists build vaccines before disease-causing pathogens emerge. , has shown promising results in mice.
Research by the Universities of Oxford and Cambridge in the UK and the California Institute of Technology in the US shows that the vaccine recognizes specific regions of eight coronaviruses, including SARS-CoV-2, which caused the novel coronavirus outbreak. states that it works by training the body's immune system. Some are currently circulating in bats and could jump to humans and cause a pandemic.
“Our focus is to develop a vaccine that protects us from the next coronavirus pandemic, so that we can be prepared before the pandemic starts,” said Dr. said author Rory Hills. report.
For example, new vaccines do not contain the SARS-CoV-1 coronavirus that caused the 2003 SARS outbreak, but they still induce an immune response against that virus.
“We have developed vaccines that provide protection against a variety of coronaviruses, including coronaviruses that are still unknown,” Hills said.
The key to its effectiveness is that the specific viral region targeted by the vaccine also appears in many related coronaviruses. Training the immune system to attack these areas provides protection against other coronaviruses not included in vaccines, including those not yet identified.
“We don't have to wait for new coronaviruses to emerge. We know enough about coronaviruses and the different immune responses to them that we can start developing protective vaccines against unknown coronaviruses now.” Professor Mark Howarth from the University of Cambridge's School of Pharmacy, lead author of the report, said:
“During the last pandemic, scientists did a great job of quickly producing a highly effective coronavirus vaccine, but the world still faces a massive crisis with a huge number of deaths. “We need to think about how to make it even better in the future, and pre-manufacturing vaccines is a strong part of that,” he said.
The new “quartet nanocage” vaccine is based on structures called nanoparticles, spheres of proteins held together by incredibly strong interactions. Chains of different viral antigens are attached to the nanoparticles using a new 'protein superglue'. These chains contain multiple antigens, which train the immune system to target specific regions common to a wide range of coronaviruses.
The latest study demonstrated that the new vaccine elicited a broad immune response even in mice pre-immunized with SARS-CoV-2.
The new vaccine is much simpler in design than other broadly preventive vaccines currently in development, and researchers believe it will accelerate the move to clinical trials.
The basic technology developed through scientific collaboration could also be used to develop vaccines to protect against many other health problems. It is said to be an improvement on previous work by a group from the University of Oxford and the California Institute of Technology to develop a new all-in-one vaccine against the coronavirus threat.
Traditional vaccines contain a single antigen to train the immune system to target one specific virus, experts say, and can be used against a variety of existing coronaviruses or newly emerging pathogens. There is a possibility that it cannot be defended against.
The latest research was funded by the UK's Biotechnology and Biological Sciences Research Council.
Sources 2/ https://www.indiatoday.in/health/story/covid-19-all-in-one-vaccine-prove-effective-against-all-coronaviruses-2536042-2024-05-07 The mention sources can contact us to remove/changing this article |
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
to request, modification Contact us at Here or [email protected]