Health

Canadian researchers are testing breakthrough approaches to treating Parkinson’s disease.National life

Researchers in Toronto-Canada are testing new approaches to treating Parkinson’s disease that they hope can slow or even stop the progression of Parkinson’s disease.

The method uses targeted ultrasound to open the blood-brain barrier and deliver therapeutic agents to specific areas of the brain. No cutting or drilling required.

Experts at the Sunnybrook Health Science Center and University Health Network in Toronto say it is the first time in the world to use targeted ultrasound to treat progressive neurodegenerative conditions in this way.

This technique allows MRI-guided ultrasound to reach deep into major areas of motion known to be affected by Parkinson’s disease.

“How to overcome that blood-brain barrier has been a major concern in neuroscience for decades,” said research co-principal researcher and Sunnybrook’s Harkway Center for Neuromodulation. Says Dr. Nirlipsman, director of the.

“Some of the areas to which this is particularly relevant are in conditions such as Parkinson’s disease and Alzheimer’s disease, and although there may be effective treatments that may work in animal and other models. , Amount we can’t put them into the brain enough. “

The blood-brain barrier protects the brain from toxins, but it can also block potentially useful drug therapies and treatments such as chemotherapy, antibodies, stem cells, and gene therapy.

Phase I of the clinical trial began at the end of summer with Pat Wilson, 56, the first of three patients who tested this method.

The idea was daunting at first, she admits from her home south of Barry, Ontario.

“I was very overwhelmed by it. I thought,’Oh, my goodness. Why should I be the first?'” Says Wilson, whose late father also had Parkinson’s disease. ..

“But it’s a little cool to get involved in that. If you can go somewhere and work for someone else, that’s great.”

Wilson says he was diagnosed in February 2013 after noticing the symptoms about a year ago.

A former school secretary was forced to retire last year because of easy-to-read writing and inability to use computers efficiently. She says that increased stress and malaise also made it difficult to increase productivity.

Lipsman says he is treating a third patient and hopes to hire another three. Exam participants must be between 35 and 73 years old.

Each patient receives three treatment sessions, each session running every two weeks. Clinical imaging is then performed 1, 3, and 6 months after the last focused ultrasound procedure.

There is currently no cure for Parkinson’s disease. Parkinson’s disease causes tremors, stiffness, slowness of movement, and other disability symptoms.

Experts have crossed the blood-brain barrier with treatments targeting Alzheimer’s disease, brain tumors, and amyotrophic lateral sclerosis (also known as ALS or Lugeric’s disease). However, Lipsman says this is the first target for Parkinson’s disease.

Risks include bleeding, cerebral edema, and potential harm to important brain functions.

Lipsman states that he already has “quite compelling data” that the procedure is safe, but the main goal of the Phase I trial is to establish it clearly.

Wilson says he hopes that advances in research will lead to better results for patients with Parkinson’s disease and is afraid that her children and grandchildren may one day develop the disease.

“But if so, it will probably be a better treatment for them,” she says.

“That’s why I’m doing it.”

This report by The Canadian Press was first published on October 30, 2020.

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: cgurgu@internetmarketingcompany.BizWebsite: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos

Pictures Credit