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New vaccine trials show promise in fighting meningitis | Health News
Phase 3 trials have shown that the NmCV-5 vaccine can induce an immune response against five major meningococcal strains.
new meningitis vaccine Trials in two African countries showed promise in combating the disease, inducing an immune response against five major strains.
A phase III randomized trial was conducted with 1,800 people in the West African countries of Mali and The Gambia, according to a new study released Wednesday by the New England Journal of Medicine.
The investigational NmCV-5 vaccine is health organization path and the Serum Institute of India tested and compared the WHO-approved and licensed MenACWY-D vaccine in participants in three age groups ranging from 2 to 29 years of age.
The results showed that a single dose of NmCV-5 produced a significantly higher immune response than the licensed vaccine. The authors said they found no serious safety concerns during the study.
Co-author of the study, Ed Clark, said the researchers were “thrilled” with the findings.
“We expect NmCV-5 to provide children and adolescents with robust protection against meningitis … the new vaccine will stop a devastating meningitis epidemic in the meningitis belt,” Clarke said in a statement. It will be an important tool for prevention,” he said.
Meningitis is inflammation of the protective membranes and tissues that cover the spinal cord and brain and is caused by various types of bacteria, fungi, parasites, and viruses.
Symptoms of this disease include nausea, vomiting, fever and neck pain. It is estimated that about 250,000 people die each year from meningitis.
“Avoid catastrophic consequences”
“Epidemic preparedness is a step forward in providing affordable and accessible vaccines to meningitis-prone areas. It should be a public health priority to prevent meningitis and would be a game-changer in the fight against meningitis,” said study co-author Ama Umeshi.
Bacterial meningitis is the most common form of the disease, which can be fatal within 24 hours and cannot be treated at home, according to the WHO. Although it occurs worldwide, some of the regions with the highest number of cases occur in sub-Saharan Africa.
A roadmap by WHO called Beat meningitis by 2030aims to end the epidemic of bacterial meningitis by 2030, reducing “vaccine-preventable bacterial meningitis” by 50 percent and deaths by 70 percent.
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